Pep Guardiola's side were beaten 3-2 by the Eagles in this fixture last term, but have only lost two of their subsequent 20 home league games.
Palace for their part were victorious when they visited Manchester earlier this season winning 2-1 at Old Trafford, but remain rank outsiders for this weekend's clash.
Latest Odds
City are the shortest-priced team to win this weekend in the Premier League with Sportsbet offering them at just 1.08 to claim three points.
Palace for their part are by some distance the biggest outsiders for this round of matches in the English top flight, priced at 23.00 to win.
The draw is available at 10.00.
Manchester City vs Crystal Palace Team News
City have no new injury concerns as they look for their sixth consecutive win in all competitions. Aymeric Laporte and Leroy Sane remain long-term absentees.
Palace by contrast have a long list of players missing including suspended midfielder Luka Milivojevic, while Cristian Benteke, Patrick Van Aanholt, Mamadou Sahko and Andros Townsend are all set to be out injured.
Manchester City vs Crystal Palace Preview
Prior to last season's surprise defeat, City had suffered few problems when hosting Crystal Palace, winning their five previous home meetings by an aggregate score of 22-1.Guardiola's men head into this match in strong scoring form having netted 17 goals in their five successive wins, and despite Liverpool boasting a healthy lead at the top of the table, City remain by far the top scorers in the division.
By contrast, Palace have struggled in the final third, with no side scoring fewer than the 20 goals netted by Roy Hodgson's men this term.
The Eagles have been particularly poor in the first halves of matches, scoring a paltry four goals before the break all season. City will therefore feel confident of leading at half-time and should be backed to do so.
Tips and Predictions
The hosts are priced at 1.33 to be ahead after the first 45 minutes and at 1.45 to score over 2.5 goals and they have done in seven of their last 10 games.Combining these two selections gives us odds of 1.80 and this seems a shrewd angle from which to get City onside.
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